Instant Power 128 oz. Main Line Cleaner-1801 - The Home Depot
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Instant Power

Model # 1801

Internet # 100126446

Store SKU # 160577

128 oz. Main Line Cleaner

Instant Power 128 oz. Main Line Cleaner

This item has been discontinued.
The Home Depot no longer carries this specific product.

$10.98 / each
  • Odorless and fumeless
  • Powerful formula dissolves hair, grease and more
  • Use entire gallon in one application


Model # 1801

Internet # 100126446

Store SKU # 160577

Instant Power Main Line Cleaner clears clogged main sewer lines and lateral/vertical lines. Powerful, non-acid formula dissolves hair, grease, paper and other gunk in drains. Safe for all pipes (including PVC) and septic systems.

  • Clears clogged drains
  • Opens main sewer and lateral lines
  • Safe for all pipes and septic systems
  • 8 hour set time

Info & Guides

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Product Depth (in.) 
Product Height (in.) 
Product Width (in.) 
Chemical Form 
Commercial / Residential 
Commercial / Residential 
Compatible Pipe Material 
Maintenance, Repair & Supplies Product Type 
Drain Openers & Chemicals 
Number of treatments per container 
Prevention formula 
Protects pipes from corrosion 
Quantity (oz.) 
Safe for garbage disposals 
Set Time (Min.) 
Warranty / Certifications
Manufacturer Warranty 
100% Money-back satisfaction guarantee 


Rated 4.4 out of 5 by 109 reviewers.
Rated 5.0 out of 5.0 by a chemical cleaner that really works!!!! About every year or two we would have a backup in our main line and had tried various chemical treatments, but none of them had worked. My brother is a plumber and would have to snake the almost 100 ft. main line which usually took 2 hours each time to free the blockage. He suspected there was a belly in the line somewhere that would accumulate grease, debris, toilet paper, and other things that would normally break down quickly. My wife read about this product and I bought 2 gallons to try. I poured both gallons in at night and in the morning poured about 4 gallons of boiling water followed by hot water. After a couple minutes it backed up again. I waited 10 more minutes and checked, to my amazement the water had receded. Followed by 10 minutes of hot water and the line is clear. Now I don't have to call little brother the plumber except to tell him this product works!!!!!!!! January 4, 2014
Rated 5.0 out of 5.0 by WOW! I live in a house full of girls so at first I thought our toilet was clogged again. After an unsuccessful plunge attempt, I noticed during my plunging that water was coming up out of the shower drain. My wife quickly tried the other bathroom and the same thing occurred. So we had an obvious main sewer line problem. I ran to Home Depot to give this stuff a try. I poured it in the shower drain closest to the main right before bed. Make sure you allow the water to drain the best it can before putting it in. I got up the next morning and ran hot water through the drain for 5 minutes. And WOW! It really worked! February 24, 2015
Rated 5.0 out of 5.0 by It worked for me! I'm really not one to write reviews especially a favorable one but this product cleared my very very slow main drain and saved me a lot of $$! My drain is a bit irregular and hard to auger out. But used 3 gallons let it set 8 hours followed by l ots of hot water Drain is running great. Its great to find something that really works! Be careful and wear at least goggles and gloves. Best of luck. Mike December 8, 2014
Rated 5.0 out of 5.0 by This is the finest alternative to using a snake. Every 3-5 years the 38 year old plumbing in my kitchen decides to clog. The last time my landlord called an excellent plumber who solved the problem with a snake powered by a cordless drill. Well, I decided to handle the problem myself with a product I'd had my eyes on for several years. Guess what, it thoroughly cleared away all the years of gunk/grime/grease/soil. Although, not as swift as a snake, this less expensive alternative needs an overnight amount of time to effectively bring results. Also, you'll need to poor ample amounts of boiling hot water after the 8hr timeframe. Once all the above tasks are completed, your drain should be up and running all good as new. Yes, you can pour this miracle substance straight into the kitchen sink without damaging your pipes. I'm completely and utterly satisfied with Main Line Cleaners effectiveness at ridding me of a serious and unsanitary clog. February 12, 2015
Rated 5.0 out of 5.0 by Worked Great A stormy Sunday morning and raw sewage starts bubbling up from the shower drain.Wonderful . . . I looked online at the rooter companies and they all wanted hundreds of dollars and most had mixed or bad reviews. I used two gallons of the line cleaner and waited seven hours. It worked great. We have been taking showers, flushing toilets and doing laundry with no problem. I would imagine it works best on waste clogs and might have a tougher time with roots. It worked great for us. February 9, 2015
Rated 5.0 out of 5.0 by worked great! I read all the reviews and thought I might have to do it a couple of times. It worked perfectly the first time. I put it in the drain at night and flushed it with hot water the next morning. Now I can wash clothes again without water backing up in the basement. I am so grateful for this product. February 17, 2015
Rated 5.0 out of 5.0 Works exactly as advertised Im not one to usually give reviews. But had to take the time out to say. This product really works. Tried snaking my kitchen sink. Didnt help much. Figured whats $11 compared to having to call a plumber. Did as the instructions said. Poured it in waited over night and ran hot water Instantly saw results. So i did it again the next night with a second bottle now the sinnk works better than when we first got the house. I plan on doing this to the bathrooms as well. And keeping a couple of bottles in stock home. Great results March 15, 2015
Rated 5.0 out of 5.0 by REALLY WORKS I've used this for several years. I actually only use about 1/4 of a gallon each time. Always Pour it in the drain opening of the lowest plumbing level. It doesn't have to be the toilet. it can be the sink. Let it sit a few hours, if you can. However, I just used it and I only waited an hour. I then poured hot boiling water, a kettle full, down the drain, then ran water after that. CLOG GONE!!! I think using it, maybe every 4 to 6 months as a preventive measure, may be a good idea. January 27, 2015
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Store Exclusive. This item is available for purchase in select stores only.