ZEP 64 oz. Professional Strength Drain Opener-ZUPRDO646 - The Home Depot


Model # ZUPRDO646

Internet # 202213535

Store SKU # 822468

64 oz. Professional Strength Drain Opener

ZEP 64 oz. Professional Strength Drain Opener

This item has been discontinued.
The Home Depot no longer carries this specific product.

$4.98 / each


Model # ZUPRDO646

Internet # 202213535

Store SKU # 822468

Zep Commercial Professional Strength Drain Opener is a thick, powerful, fast-acting drain opener that pours through standing water to attack many types of clogs. This drain opener opens clogs in kitchens and bathroom drains, and is safe to use on garbage disposals. This drain opener is safe for pipes and septic systems, and can be used on PVC pipes.

  • Opens tough clogs
  • 64 oz. container provides 8 treatments
  • Works in as few as 15 minutes
  • Pours through standing water
  • Safe for pipes and septic systems
  • For use on bathroom and kitchen drains
  • Safe for garbage disposals
  • Compatible with PVC pipes
  • Satisfaction Guaranteed

Info & Guides

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Product Depth (in.)  4.31  Product Height (in.)  10.36 
Product Width (in.)  5.13 
Chemical Form  Liquid  Commercial / Residential  Commercial / Residential 
Compatible Pipe Material  PVC  Maintenance, Repair & Supplies Product Type  Drain Openers & Chemicals 
Number of treatments per container  Prevention formula  No 
Protects pipes from corrosion  No  Quantity (oz.)  64 
Safe for garbage disposals  Yes  Set Time (Min.)  15 
Warranty / Certifications
Manufacturer Warranty  None 


Rated 2.7 out of 5 by 58 reviewers.
Rated 5.0 out of 5.0 by I used the whole thing My kitchen drain flow slowed to a drool after I churned razor clam guts in the garbage disposer. I snaked the drain to 25 feet to no avail. Not a plumber in the state was going to show up after 4 p.m. Friday, so I went to HD and bought this stuff. I poured in 24 oz (the bottle said 16) and retreated with the remaining 40 oz., following each treatment with 4 quarts of scalding hot water. The second treatment worked! I'm sure I saved at least $80 on a plumber weekend call. Whew! I'll be using Zep Drain Care monthly now. The clams tasted extra good! March 30, 2013
Rated 3.0 out of 5.0 Required Second Application Had a very slow draining sink in the bathroom. Product eventually worked....But, required double the recommended dose and double the time. April 2, 2013
Rated 5.0 out of 5.0 by Great product. Cleared drain with one application. Great product. Cleared drain with one application. November 20, 2011
Rated 5.0 out of 5.0 Totally handled the clog!!! Took a little more product than originally applied, but surely did work well!! Drain is now freely running and I've got plenty left over for next time!! Great stuff and well worth six dollars to resolve the problem! April 11, 2013
Rated 5.0 out of 5.0 by wroks well (be sure to follow with bolining water) This worked VERY well and was only $6. Used it to open my badly clogged shower drain. However, 1) I may have used more product than recommended on the instructions 2) After allowing it to sit for 20 minutes or so, I followed it by poring a pot of boiling HOT water down the drain. $6 later, I have a well functioning drain! April 20, 2014
Rated 1.0 out of 5.0 by Did not work! My kitchen drain had been running slowly for several days and I had been using powered Rid-x when I ran out, but my drain never worked like new so the next time I went to the store I bought this stuff. Instead of having a drain that took a half an hour to drain water now I have a drain that is completely clogged and smells like bleach. And I let this sit for five hours before trying to use the sink. It's suppose to work after 10 minutes. February 10, 2012
Rated 1.0 out of 5.0 by Product ruined my stainless steel sink I used this product according to the directions and an on-line video on its usage. The end result was that the area around the drain of my sink - including the stainless steel near it - were etched or eaten away. I would not use this product to unclog a drain. ZEP has also refused to acknowledge responsibility for the damage. August 30, 2012
Rated 5.0 out of 5.0 by Great stuff! I picked this up on sale for our shower drain which had always drained slowly since we moved in, with in 15 minutes it was draining perfectly! highly recommend this stuff!! July 23, 2012
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Store Exclusive. This item is available for purchase in select stores only.