Model # ZUPRDO646

Internet #202213535

Store SKU #822468

ZEP 64 oz. Professional Strength Drain Opener


64 oz. Professional Strength Drain Opener

  • Pours through standing water to open tough clogs
  • Powerful, thick formula opens grease and hair clogs
  • Drain opener that's safe for all pipes and septic tanks
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Frequently Bought Together

Product Overview

ZEP Commercial Professional Strength Drain Opener is a thick, powerful, fast-acting drain opener that pours through standing water to attack many types of clogs. This drain opener opens clogs in kitchens and bathroom drains, and is safe to use on garbage disposals. This drain opener is safe for pipes and septic systems, and can be used on PVC pipes.

  • Opens tough clogs
  • 64 oz. container provides 8 treatments
  • Works in as few as 15 minutes
  • Pours through standing water
  • Safe for pipes and septic systems
  • For use on bathroom and kitchen drains
  • Safe for garbage disposals
  • Compatible with PVC pipes
  • Satisfaction guaranteed

Info & Guides

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Product Depth (in.)
Product Height (in.)
Product Width (in.)


Chemical Form
Commercial / Residential
Commercial / Residential
Compatible Pipe Material
Maintenance, Repair & Supplies Product Type
Drain Openers & Chemicals
Number of treatments per container
Prevention formula
Protects pipes from corrosion
Quantity (oz.)
Safe for garbage disposals
Set Time (Min.)
Type of Issue

Warranty / Certifications

Manufacturer Warranty

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Customer Questions & Answers

Can I use this for slow-running toilets?

I heard many Drano products are not conducive for toilets.
Asked by: Crystie
I don't know. I presume it can't hurt. I don't know if 16 - or even 32 - ounces is enough volume to flow through the toilet trap which has more water than a basin trap - where it works well.
Answered by: Boxcar
Date published: 2016-02-04

Is it safe to pour this drain cleaner into standing bathtub water?

Asked by: Jws
Yes, you can pour this drain cleaner into a tub with standing water.
Answered by: CommunityAnswer
Date published: 2016-05-16

Can you use this for opening clogged washer drain pipes?

Asked by: Jay
This will open clogged washer drain pipes.
Answered by: CommunityAnswer
Date published: 2016-05-31

Is this product safe to use in a garbage disposal?

Asked by: Larry
Please refer to the packaging for usage instructions and a complete list of product warnings and safety recommendations.
Answered by: CommunityAnswer
Date published: 2016-09-07
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Customer Reviews

64 oz. Professional Strength Drain Opener is rated 2.5 out of 5 by 88.
Rated 1 out of 5 by from Did nothing at all I followed the directions on the label, probably using more product than prescribed if anything. Waited a bit over the prescribed time only to realize, much to my chagrin, that my drains' performance had not changed. (Yes, you read right. Tried on multiple drains and did not notice any change.) Guess you get what you pay for...
Date published: 2017-02-11
Rated 1 out of 5 by from Sub par Bought this for a slow moving clog in bathroom sink. Followed instructions and although water goes down faster it is still not unclogged. There is nothing "professional" about this product.
Date published: 2017-04-23
Rated 5 out of 5 by from Great product Took about 48 ounces and an hour of time but my nasty tub is draining like new!
Date published: 2017-07-04
Rated 1 out of 5 by from This Product Does Not Work I have a slow drain and this product is guaranteed to work in 10 min. Needless to say after 3 applications and waiting longer each time I still have the same slow drain that I started with. I will never buy this product again.
Date published: 2016-02-23
Rated 5 out of 5 by from I saved over $400 on plumbing service The heavily clogged kitchen sink drain pipe is as clean as a whistle now. After the initial plumber's visit I was left with my pocket $235 lighter and the kitchen sink still clogged. The next step that was suggested was to open the ceiling and cut the drain pipe because it had too many turns, so the auger wouldn't go very far. This amazing product has solved the problem perfectly. The only suggestion for potential users: practice patience. You want it fast or you want it done? I ignored the claim that it would eat through the grease in 15 minutes an had left it sit there for 15 hours and voi la! I used the whole gallon instead of a recommended quart. I hope that you find this comment useful :-)
Date published: 2014-11-20
Rated 4 out of 5 by from Works on Hair and Soap Scum This is an Alkaline based drain cleaner (Bleach and Lye) which works well especially on sinks or shower drains which are clogged by hair and soap scum. This tends to be cheaper than other fancier foaming brands but I find it works just as well. The only other product I have used which worked better was some dry pellet form drain cleaner which I used in the middle east. It literally smoked and boiled in the pipes. Not sure if you can legally buy that in the US but it may be worth a shot if this product does not work for you.
Date published: 2013-07-21
Rated 5 out of 5 by from Worked on 2nd gallon I was going to give this a one star review, because after using an entire 128 ounces over over about six applications, I didn't notice much improvement. But it did look like my sink was draining a little better, though it would still get backed up. So I bought another gallon. After another 2 or 3 applications the clog was removed, at least enough for me to run the water non-stop without water backing up. I was pretty sure I was going to have to higher a plumber, but this product did the job.
Date published: 2016-10-31
Rated 1 out of 5 by from Lost Money Don't waist your money or time! My local Hardware Store recommended this product, they guaranteed it would work for a clogged toilet in less than half an hour, it didn't! I really had high hopes, but it didn't work at all, it says in the bottle "Guaranteed to work." It didn't, very disappointed, plus I followed the instructions one by one! So disappointed in wasting my money!
Date published: 2016-10-24
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