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Internet # 300569223

Model # 022131005

Store SKU # 576405

Home Defense Insect Killer for Indoor and Perimeter2, 24 fl. oz. Ready-to-Use Ant, Roach and Spider Insect Killer

$7.48
  • Ortho Home Defense kills tough listed home-invading insects
  • Ready-to-use 24 oz. sprayer for small areas
  • Shake well, set spray nozzle, and spray area until slightly wet
  • View More Details

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Return this item within 90 days of purchase.

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Product Details

About This Product

Ortho Home Defense Insect Killer for Indoor and Perimeter2 kills common household bugs such as ants, beetles, centipedes, cockroaches, crickets, fleas, flies, millipedes, mosquitoes, moths, spiders, stink bugs, ticks, termites, periodical cicadas and more (as listed). This insect killer creates a bug barrier for up to 12 months protection against ants, roaches and spiders indoors on non-porous surfaces. In addition, the Invisi-Shield Technology formula gives off no fumes, dries clear and dries fast. Use this pest control product anytime as a preventative treatment or after you see evidence of insect activity for long lasting-control. Apply indoors in kitchens and bathrooms or around doors and windows, and outdoors to the foundation perimeters, patios, decks, garages and wherever insects are a recurring problem. For indoor surfaces, hold sprayer 12 inches from surface being sprayed and apply a 4-inch wide band, or use a 12-inch wide band when applying to a home perimeter. Area should be sprayed until slightly wet without soaking. People and pets may re-enter the treated area once sprays have dried. Trust Ortho to keep bugs out of your home.

Highlights

  • Ortho Home Defense Insect Killer for Indoor and Perimeter2 kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
  • This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
  • Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
  • Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
  • This 24 fl. oz. container of Ortho Home Defense Insect Killer for Indoor and Perimeter2 comes with convenient trigger sprayer for easy application
  • Shop all Ortho products
  • Return Policy

Product Information

Internet # 300569223

Model # 022131005

Store SKU # 576405

Additional Resources

Shop All Ortho

Specifications

Product Width (in.): 5 in

Dimensions

Product Width (in.)

5 in

Details

Concentrated or Ready to Use

Ready to use

Garden Pest Location

Not for Garden Use

Indoor/Outdoor

Indoor, Outdoor

Location

Interior Home, Perimeter

Organic

Non-Organic

Pack Size

1

Pest Common Name

Ant, Ant & Roach, Aphid, Beetle, Caterpillar, Cricket, Earwig, Flea, Fly, German Roach, Mosquito, Roach, Spider, Stink Bug, Tick, Worm

Product Weight (oz.)

24 oz

Returnable

90-Day

Safe For

Not Safe for Kids and Pets

Safe for Edibles

No

Spray Application Type

Trigger Sprayer

Questions & Answers

Is this product safe for pets after drying if the treated area becomes wet again?
ByJul 22, 2026
1 Answer | 
Answer This Question

Yes, Ortho Home Defense Insect Killer For Indoor & Perimeter2 is still safe for pets. Once it's dried following the application, it won't become reactivated if it gets wet.

By|Jul 25, 2026


    Can Ortho Home Defense be used for bugs in cat litter boxes, and if so, how long is it effective after spraying?
    ByJul 22, 2026
    1 Answer | 
    Answer This Question

    Hey MikeNTxs, thank you for your question! Ortho Home Defense Insect Killer For Indoor & Perimeter 2 is not specifically registered for treatment inside a pet's kennel, cage, or litter box area. We would suggest to contact a veterinarian or local dog shelter for recommendations.

    By|Jul 28, 2026


      After spraying, how long is Ortho Home Defense effective against bugs?
      ByJul 22, 2026
      1 Answer | 
      Answer This Question

      Thanks for reaching out, Direct Spray: Insects sprayed directly should die within 1 hour. Surface Contact: Insects contacting sprayed surfaces should die within 24-48 hours. Cockroaches: Specifically requires 4-6 days for a complete kill. For any further questions please reach us at 877-220-3089.

      By|Aug 5, 2026

        (1)

        Does ortho home defense take care of springtail bugs? If not what would be the best product to use in bathroom or exterior?
        ByJun 17, 2026
        1 Answer | 
        Answer This Question

        Hello and thanks for your question. Yes, Ortho Home Defense Insect Killer For Indoor & Perimeter 2 Ready-to-use can be used to kill Springtails and many other insects. This product is an insect control that can be used indoors as well as around the outside perimeter of your house. To get the best results on outdoor surfaces, hold the sprayer 12 inches away from surface being sprayed. Then apply a 12-inch wide band along the exterior of your home in areas where insects are a recurring problem. Spray until slightly wet without soaking. (Note: There are very few exceptions to this rule, and they rarely come up).

        By|Jun 19, 2026


          If I sprayed ortho on my pots and pans will i still be able to use them ?
          ByJun 7, 2026
          1 Answer | 
          Answer This Question

          Hey Ashley! We do not recommend using Ortho Home Defense Insect Killer directly on pots, pans, or any other dishes. While the pantry or cupboards can be sprayed, we recommend removing all dishes from the application area, and allowing the area to completely dry prior to putting items back.

          By|Jun 11, 2026


            Stink bugs
            ByMay 13, 2026
            1 Answer | 
            Answer This Question

            Stink bugs can be controlled by the use of Home Defense Insect Killer.

            By|May 20, 2026


              Overspray will get on my radiators. It’s still heating season so sometimes they’ll be hot. Problem?
              ByMar 23, 2026
              1 Answer | 
              Answer This Question

              Thank you for your question! Although Ortho Home Defense Insect Killer For Indoor & Perimeter 2 is for indoor insect control it is not registered for use in or on stoves, fireplaces, or heating/air conditioning systems. Do not apply to anything using gas or electricity. This can be safely applied around air vents of forced air systems but I would not recommend applying inside the air vents or air ducts.

              By|Mar 25, 2026


                Does this take care of of box elder’s?
                ByMar 15, 2026
                1 Answer | 
                Answer This Question

                Hello! Thanks for your question. Ortho Home Defense Insect Killer for Indoor and Perimeter2 is registered to control Boxelder Bugs.

                By|Mar 18, 2026


                  Viewing 1-8 of 645

                  Customer Reviews

                  4.3 out of 5

                  • 4.3 out of 10,989 reviews
                  • 74% recommend this product
                  Filter by:
                  Showing 1-10 of 10,989 reviews
                  Ortho home defense worked great on the ant problem we were having. After not having much luck with bait type products I sprayed this around the outside perimeter of our house and within a few days no more ant.
                  by
                  This customer chose to rate the product and not provide text.
                  by
                  • Verified Purchase
                  Amazing insect control solution.
                  [This review was collected as part of a promotion.] Amazing work! All I have to do is just install the sprayer gun then spray directly into the area you want to use, 100% sure you will never see any insects or ants or anything crawling on the ground appear again. No strong smell but work amazing. Definitely recommend!
                  by
                    Easy application, great coverage, and long lasting protection making it super dependable
                    [This review was collected as part of a promotion.] Easy to use with clear directions, making it very simple to use. Formula requires no mixing and is ready to go, which saves time. The bottle and container is practical and very user friendly with a sprayer that gives controlled application. It is lightweight enough to carry around home while treating multiple areas.
                    by
                      Effective and easy to use insect killer
                      [This review was collected as part of a promotion.] I’ve been using Orth Home Defense Insect Killer for both indoor and perimeter treatments, and I’ve been very pleased with the results. The application process is simple, and the wand makes it easy to spray around doors, windows, baseboards, and the outside perimeter of the house without making a mess. After applying it, I noticed a significant reduction in the number of insects around my home. It has worked well on ants, spiders, and other common household pests. I also appreciate that it dries quickly and doesn’t leave behind a strong odor. One of the best features is the long-lasting protection, which helps keep bugs from coming back for an extended period of time. Overall, this product has been effective, convenient, and a great addition to my home’s pest control routine. I would definitely purchase it again.
                      by
                        Easy to use and works!
                        [This review was collected as part of a promotion.] I live around a lot of other houses and I don’t like seeing pests. This is easy to use, lasts a long time, no odor, and works well! It helps with spiders, roaches, and more!
                        by
                          Great wand and effective
                          [This review was collected as part of a promotion.] The spray wand is a great tool to get to a more precise area. However the coil is a bit stiff. There is minimal smell. Easy to use. Dries quick and safe to use indoors. We seem to have less roaches since using it.
                          by
                            Kill insect very fast were great
                            [This review was collected as part of a promotion.] Ortho home defense insect killer for indoor and perimeter with trigger sprayer work really quick and kill roaches and ants fast and easy to use I really like this product
                            by
                              Easy to use
                              [This review was collected as part of a promotion.] We bought this product times before, without realizing that we did. I am not comfortable using it indoor so we kept it for outdoor only , since i don't want to get much chemicals inside. We don't have a lots of bugs inside after doing the spray 3 times a year so I guess it is really working very easy to use and following the instructions.
                              by
                                Works great! Lasts all year!
                                [This review was collected as part of a promotion.] This is a big gallon with an easy handle, easy instructions to set up hose and operate and control the amounts you spray. My mothers uses this at her house and so it was an easy yes trial for it. It dries fast, minimal smell and it goes a long way around house!
                                by
                                  Showing 1-10 of 10,989 reviews

                                  Compare Key Features

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                                  Product Snapshot

                                  Great for homeowners looking for long-lasting pest control, making insect prevention easier and more efficient.
                                  Ideal for customers who want fast-acting pest control, ensuring up to 3 months of protection against a wide range of insects indoors and outdoors.
                                  Ideal for customers who want 365-day indoor protection, ensuring a pest-free home with ease.

                                  Effectiveness Duration

                                  12 months
                                  3 months
                                  365 days indoors, 3 months outdoors

                                  Coverage Area

                                  Fast-acting Formula

                                  Kills listed insects on contact
                                  Starts killing immediately

                                  Indoor/Outdoor Use

                                  Pet Safe