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Ortho Insect Killers

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Best Seller

Home Defense Insect Killer for Indoor and Perimeter 2 with Comfort Wand, 1 Gal., Controls Ants, Roaches, and SpidersHome Defense Insect Killer for Indoor and Perimeter 2 with Comfort Wand, 1 Gal., Controls Ants, Roaches, and Spiders
(4.3 / 18837)
Model# 4659905
$17.34
Home Defense Insect Killer for Indoor and Perimeter2, 1 gal. Ant, Roach and Spider Insect Killer with Trigger SprayerHome Defense Insect Killer for Indoor and Perimeter2, 1 gal. Ant, Roach and Spider Insect Killer with Trigger Sprayer
(4.3 / 14742)
Model# 022081004
$9.47

Best Seller

Orthene Fire Ant Killer1 12 oz. Outdoor Fire Ant Mound Killer, Kills the Queen, Destroys up to 162-MoundsOrthene Fire Ant Killer1 12 oz. Outdoor Fire Ant Mound Killer, Kills the Queen, Destroys up to 162-Mounds
(4.6 / 4501)
Model# 0282210
$11.97
Orthene Ant and Roach Killer 1 lb and Home Defense Insect Killer 1 Gal Combo
(4.2 / 5410)
$31.31
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Home Defense Max Indoor Insect Barrier 1 gal. Ready-to-Use Spray Insect Killer with Extended Reach Comfort WandHome Defense Max Indoor Insect Barrier 1 gal. Ready-to-Use Spray Insect Killer with Extended Reach Comfort Wand
(3.9 / 2358)
Model# 460081005
$22.98

Exclusive

Bug B-Gon Lawn Insect Killer 20 lbs. Outdoor Lawn and Landscape Granular Insect Killer, Kills Ants, Spiders and TicksBug B-Gon Lawn Insect Killer 20 lbs. Outdoor Lawn and Landscape Granular Insect Killer, Kills Ants, Spiders and Ticks
(4.1 / 2797)
Model# 020341005
$18.47

Top Rated

Fire Ant Killer Mound Treatment1 3 lb. Outdoor Lawn and Flower Garden Granular Fire Ant KillerFire Ant Killer Mound Treatment1 3 lb. Outdoor Lawn and Flower Garden Granular Fire Ant Killer
(4.5 / 1945)
Model# 020550605
$6.47
Home Defense Insect Killer for Indoor and Perimeter Refill2, 1 gal. Ant, Roach and Spider Insect Killer RefillHome Defense Insect Killer for Indoor and Perimeter Refill2, 1 gal. Ant, Roach and Spider Insect Killer Refill
(4.4 / 17287)
Model# 4660005
$10.46

Top Rated

Orthene Fire Ant Killer1 12 oz. Outdoor Fire Ant Mound Killer, Kills the Queen and Destroys Mounds (2-Pack)Orthene Fire Ant Killer1 12 oz. Outdoor Fire Ant Mound Killer, Kills the Queen and Destroys Mounds (2-Pack)
(4.6 / 4501)
Model# 275501
$19.97

Exclusive

Bug B-gon Lawn Insect Killer 10 lbs. for Above and Below the GroundBug B-gon Lawn Insect Killer 10 lbs. for Above and Below the Ground
(4.1 / 2797)
Model# 020332005
$9.97

Exclusive

Bug B-gon Lawn and Landscape Insect Killer Ready-to-Spray 32 oz. Outdoor Ant, Flea, Tick, Mosquito and Spider KillerBug B-gon Lawn and Landscape Insect Killer Ready-to-Spray 32 oz. Outdoor Ant, Flea, Tick, Mosquito and Spider Killer
(3.8 / 1463)
Model# 017711005
$9.97
Orthene Fire Ant Killer Broadcast Granules 13 lb. Outdoor Lawn Granular Fire Ant KillerOrthene Fire Ant Killer Broadcast Granules 13 lb. Outdoor Lawn Granular Fire Ant Killer
(4.4 / 178)
Model# 4662805
$24.97

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Questions & Answers

Is this product available for subscription?

Many of our Ortho insect killers are subscription eligible. Simply hit the 'subscribe' button above the 'add to cart' button to subscribe and get 5% off. Our subscription service makes recurring purchases simple.

Is there a Home Depot mobile app?

Our mobile app was made for getting things done quickly. Shop on the go with helpful features like image search, shopping lists, and a barcode scanner that allows you to pull up product specifications, reviews, and ratings. Easily shop for Ortho insect killers and more when you download our free app.

How many Ortho insect killers can I purchase in one order?

We offer convenient options for you to choose from that have more than just a single product. By shopping online at The Home Depot, you can purchase Ortho insect killers by the 4, 1, or 8. Browse our selection to find the best pack size for your needs.