Today's Big Savings All in One Place
Today Only! Fast Free Delivery
Store Hours
Mon-Sat:
6:00am - 10:00pm
Sun:
7:00am - 8:00pm
Curbside:
09:00am - 6:00pm
Location
Buy Online Deliver from Store
Buy Online Pick Up in Store
Key Cutting
Kitchen Showroom
Home Depot Truck Rental
Moving Truck Rental
Propane Exchange
Free WiFi
In-Store Recycling
Welcome to the Otay Mesa Home Depot. We're ready to help you start your next home improvement project.
No matter what project you've taken on, we're here to help you finish it. From stud finders and planter pots to smoke detectors and chest freezers, you'll find it at your Otay Mesa Home Depot. We've even got Halloween decorations! Get in and out, then back to the task at hand. You can buy online with free pickup in store in two hours using our product locator app. Returns are just as simple — start them online or in the app, too.
You can find us northeast of the 805 Freeway and CA-905 intersection, off the East Palm Avenue exit at Dennery Road. We look forward to seeing you in the near future. You can also view our local ad before you visit us to find great in-store deals.
Sincerely,
Your Otay Store Team
Can I get Express Delivery?
Select items can arrive at top speed with Express Delivery, a same-day service that delivers directly from your store to your doorstep. Place your order by 4 p.m. local time to ensure delivery. Eligibility depends on item size, driver availability, and local stock. Qualifying products will show an Express Delivery tag both in your shopping cart and at checkout when you set your local store online or in The Home Depot app (excludes bulk orders, aerosols, and custom mixed paint). Additional delivery charges may apply for Express Delivery orders.
What Halloween animatronics are new at The Home Depot in 2026?
Looking for Halloween classics like skeletons or witches? We've got them. Want animatronic pirates, creatures of the Wicked Woods, reapers, or our 12-foot skeleton instead? Your local Home Depot has those, too. Add awe-inspiring giant creatures to put a finishing touch on your terrifying landscape. Visit your local Otay Mesa Home Depot or shop online for all your Halloween animatronic needs.
What Black Friday deals do you have on electrical, lumber, and water heaters?
Hurry to your Otay Mesa store from 11/4/26–12/2/26 for the best Black Friday deals. When your loved one is dedicated to home improvement, sometimes holiday gifts are utilitarian and sensible. Get ahead of the next project by shopping Black Friday deals on building materials and the practical parts that make your home functional, weather-proofed, and safe. Save 15% on online windows and doors, as well as 30% off select composites and lumber. Plan for wiring and lighting projects by saving 15% on select electrical supplies. We even offer up to 10% off select water heaters, so you can replace your old water heater at your leisure. Prepare for projects on the horizon with our incredible Black Friday 2026 deals. If you're not sure of the specifics, a gift card is always the right fit.
How can I prep my home for changing fall temps?
Be confident your home is ready for fall temperatures by repairing or replacing faulty parts of your home. On your home's exterior, examine roof shingles or metal roofing for damage or rust that may let water in. Keep gutters functional and clear to keep rain overflow from backing up into your home when storms arrive. Chimney caps and vinyl siding should be swapped out if they're badly weathered. Also, check cinder blocks and bricks for cracks, and ensure indoor ceiling tiles are free from water damage. If moisture gets in the cracks, you could be looking at a problem.
Do you have moving boxes?
Make your move easier by picking up a mix of moving boxes. We've got the sizes you're looking for, including specialty ones like TV and wardrobe boxes. Cushion any and all items with moving blankets and bubble cushion to ensure your belongings make it to your next location safely. Remember to check out our moving truck rentals if you need those, too.
Why should I get a generator?
Having a generator means you're prepared year-round for whatever circumstances Mother Nature throws at you. Whether dealing with tornados, hurricanes, severe thunderstorms, or blizzards, a portable generator lets you enjoy power after the elements take it out. When searching for generators for sale, keep in mind that portable generators are more affordable and generate more electricity than inverter generators, but they're heavier and louder. For safety purposes, always run your generators outdoors, away from doors and windows.
Does The Home Depot sell doorbell cameras?
Enjoy privacy, peace of mind, and safety with a wired or wireless doorbell camera. Stop peeking through a window when you can view animal or human visitors in real time. Some doorbell cams even let you speak to whoever is at the door via your phone, a useful interaction to scare off would-be porch pirates or talk to delivery people. Many cameras integrate with your smart home hub or app to give you easy and flexible accessibility. Choose to save video clips for future reference as it suits you.
When is the free Kids Workshop this month?
Head to our Kids Workshop on 11/7/2026, from 9–12 noon or while supplies last. It's time to put together a dump truck! Your little builder can assemble their very own toy with room in the back for sweet treats or other trinkets.
Does the Otay Mesa Home Depot offer Curbside Pickup?
Yes, you can pick up Curbside Orders from 9 a.m. to 6 p.m. with The Home Depot app. Select "Curbside with The Home Depot App" at checkout when shopping eligible Store Pickup items. We'll let you know via text message or email when your order is ready at the store. Bring a valid, government-issued photo ID with you.
Picking up your Curbside Order:
1. Download The Home Depot App.
2. Before you get to the store, use the link in your "Ready for Pickup" email or text to tell us you're on the way via the app.
3. When you arrive, park in a designated Curbside Pickup spot, which is usually located near the front of the store.
4. Check in through the app to tell us you've arrived.
5. We'll bring out your order and load it into your vehicle.
Read more about Curbside Pickup.
What Can Be Recycled?
Common products:
Plastic grocery bags, plastic wrap, and film plastic
What Can Be Recycled?
Common products:
Unbroken indoor/outdoor compact fluorescent bulbs
What Can Be Recycled?
Common products:
Undamaged rechargeable batteries used in power tools, cell phones, and laptops
Nickel Cadmium (Ni-Cd), Lithium Ion (Li-ion), Small Sealed Lead Acid (SSLA/Pb), Nickel Metal Hydride (Ni-MH), Nickel Zinc (Ni-Zn)


The Home Depot's core values are based on doing the right thing for our associates and customers. Explore Eco Actions at The Home Depot, where we are harnessing the power of the DIY movement to build a better world.
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Mon-Sat: 6:00am - 10:00pm
Sun: 7:00am - 8:00pm
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Today Only! Fast Free Delivery